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TOP > NEWS > GPCR Symposium
 

GPCR symposium - Frontier on Integral Membrane Proteins in Crystal Structure Determination - (2008.2.26)

  The fiscal year of 2007 is the year of more than 2,000 citation hits of the first GPCR structure paper, “Crystal structure of Bovine Rhodopsin” was reported using SPring-8 in 2,000 as well as the 10th anniversary of SPring-8. The 2007 is the jumping year of the structure determination on human integral membrane proteins as the major drug targets; human b2-adrenergic receptor, leukotriene C4 synthase and five-lipoxygenase activating protein. We organize the symposium the integral membrane protein structure determination from the view of their application in the next decade. (Presentation language: English)

01
Dates: 2008.February 26(Tue) 9:00-17:40
After the session: Party
Venue: SPring-8 Public Relations Center Big Hall
(1-1-1, Kouto, Sayo-cho, Sayo-gun, Hyogo)
Access to SPring-8     Campus map
Contact: Resistration(free), party(3,000yen) and accommodation(2,000yen)
Please contact to Ms. Aimoto
E-mail: aimoto_at_spring8.or.jp (exchange "_at_ "to "@")
Tel: 0791-58-2815
Language: English
Host: RIKEN

Program:

1st Session Integral Membrane proteins as drug targets
09:40 - 10:10 Human Leukotriene C4 synthase H.Ago (RIKEN)
10:10 - 10:40 Neurotransmitter Transporter homologue A.Yamashita (RIKEN)
10:40 - 10:50 Coffee break
10:50 - 11:30 Multidrug recognition and pumping by bacterial multidrug transporter
- A structural view S.Murakami (Osaka Univ.)
11:30 - 12:30 How Ca2+ -ATPase pumps ions across the membrane. C.Toyoshima (Tokyo Univ.)
2nd Session GPCRs, Structure and Function as drug targets
13:30 - 13:40 Session Overview M.Miyano (RIKEN)
13:40 - 14:40 Structure and Dynamics of the Human b2 Adrenergic Receptor B.K.Kobilka (Stanford Univ.)
14:40 - 15:20 Structure and Function of Bovine Rhodopsin T.Okada (AIST)
15:20 - 15:40 Coffee break
15:40 - 16:10 Crystal Structure of Squid Rhodopsin at 2.5Å resolution T.Kouyama (Nagoya Univ.)
16:10 - 16:50 Towards Structure Determination of Human Membrane Receptors T.Kobayashi (ERATO)
16:50 - 17:30 GPCRs and Drug Discovery S.Hinuma (Takeda Pharma.)
17:30 - 17:40 Closing Remarks H.Suematsu (RIKEN)
18:00 - 19:30 Dinner for speakers and participants (SPring-8 Cafeteria)